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News - week 14 - 2008
Scientific opinion on environmental
impacts and antimicrobial resistance effects of 4 substances used for decontamination of
poultry carcasses
The Scientific Committee on Health and
Environmental Risks (SCHER) and the Scientific Committee on Emerging and Newly Identified
Health Risks (SCENIHR) jointly examined the environmental impacts of 4 chemical substances
(chlorine dioxide, acidified sodium chlorite, trisodium phosphate and peroxyacids) used to
remove microbial surface contamination from poultry carcasses.
In their joint opinion, published today,
the 2 Committees conclude that the direct discharge of chlorine dioxide, acidified sodium
chlorite and peroxyacids solutions may present a significant risk for receiving water
bodies even after dilution with the slaughterhouse waste waters. However, the risk can be
prevented by appropriate effluent treatment in a municipal waste water treatment plant. In
the case of trisodium phosphate, discharge of solutions should be managed in order to
avoid releasing phosphate into the aquatic environment, with the associated risk of
eutrophication.
The Committees also evaluated potential
residues in carcasses as a diffuse source of environmental releases. In this respect, a
low environmental risk was estimated for 4 substances. SCHER and SCENIHR assessed
the possible effect on the emergence of antimicrobial resistance through the environment
if these 4 substances were used in slaughterhouses for removing microbial surface
contamination from poultry carcasses. Their opinion complements a recent opinion of EFSA
on the possible contribution of these substances to antimicrobial resistance through food
intake.
There is currently limited evidence on the
potential of producing bacterial resistance after treating poultry with these 4 chemicals.
Nevertheless, these chemicals are able to select less susceptible strains of Salmonella
and some other pathogens. There is insufficient data to determine whether they may cause
cross-resistance to antibiotics or the selection of specific microbial groups associated
to resistance. In addition, more information is needed from the manufacturing companies on
the conditions for application of the 4 substances and the factors influencing the
efficacy of the substances.
For more information on the SCHER/SCENIHR
joint opinion please visit the following link:
http://ec.europa.eu/health/ph_risk/committees/documents/joint_o_001.pdf
For more information on the EFSA's opinion
please visit the following link:
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1178697425124.htm
Ditta
High blood glucose raises IGF-1 and
cancer risks
A new study provides compelling evidence that high GI diets increase your risk of type 2
diabetes and heart disease. There's also good evidence for links between high blood
glucose and some cancers. This is because constant spikes in blood glucose from eating
high GI gushers cause the body to release more insulin, and also increase a related
substance called insulin like growth factor one (IGF-1). Both these hormones increase cell
growth and decrease cell death, and have been shown to increase the risk of developing
cancer.
http://ginews.blogspot.com
Symposium to explore role
nanoparticles may play in disease
Two Mayo Clinic researchers who study the role nanoparticles may play in hardening of the
arteries and in the formation of kidney stones, will lead a symposium on how these
super-small particles may affect the body's physiology. The symposium will take place
April 8 at the Experimental Biology conference in San Diego.
http://www.the-aps.org/press/journal/08/18.htm
Overweight kids have fewer
cavities, new study shows
Contrary to conventional wisdom, overweight children have fewer cavities and healthier
teeth compared to their normal weight peers.
http://www.eurekalert.org/pub_releases/2008-04/uorm-okh040208.php
Brain DNA 'remodeled' in alcoholism
Reshaping of the DNA scaffolding that supports and controls the expression of genes in the
brain may play a major role in alcohol withdrawal symptoms, particularly anxiety, that
makes it so difficult to stop using alcohol by alcoholics, researchers at the University
of Illinois at Chicago College of Medicine and the Jesse Brown VA Medical Center report in
a study in the April 2 issue of the Journal of Neuroscience.
http://tigger.uic.edu/htbin/cgiwrap/bin/newsbureau/cgi-bin/
index.cgi?from=Releases&to=Release&id=2146&fromhome=1
Mayo Clinic Proceedings examines
link between bacteria in the digestive system and obesity
According to John DiBaise, M.D., a Mayo Clinic Arizona gastroenterologist and lead author
of the Mayo Clinic Proceedings article, several animal studies suggest that gut microbiota
are involved in regulating weight, and that modifying these bacteria could one day be a
treatment option for obesity.
http://www.mayoclinic.org/news2008-rst/4741.html
MU researcher links hormone
replacement therapy to breast cancer
In a recent University of Missouri study, researchers found that one of the hormones used
in HRT could be a major factor in promoting breast cancer. At the same time, the
researchers have compelling evidence that using an antibody that prevents new blood vessel
formation in tumors, or a small molecular drug, known as PRIMA, with similar properties as
the antibody may be effective in treating or preventing the negative effects of progestin.
http://www.eurekalert.org/pub_releases/2008-04/uom-mrl040108.php
USC researchers find new clues to
risk of Hodgkin lymphoma
A long-term study of twins has led University of Southern California researchers to find
potential links between Hodgkin lymphoma and levels of an immune response protein
(interleukin-12).
http://www.eurekalert.org/pub_releases/2008-04/uosc-urf040108.php
Algae could one day be major
hydrogen fuel source
As gas prices continue to soar to record highs, motorists are crying out for an
alternative that won’t cramp their pocketbooks. Scientists at US Department of
Energy's Argonne National Laboratory are answering that call by working to chemically
manipulate algae for production of the next generation of renewable fuels -- hydrogen gas.
http://www.anl.gov/Media_Center/News/2008/news080401.html
Researchers develop new method to
test for lung cancer
Researchers from Boston University School of Medicine have developed a new
"clinicogenomic model" to accurately test for lung cancer. The model combines a
specific gene expression for lung cancer as well as clinical risk factors. These findings
currently appear online in the journal Cancer Prevention Research.
http://www.bu.edu/phpbin/news/releases/display.php?id=1548
Renal artery stenting falls short
in large randomized trial
The largest-ever randomized study to evaluate the effectiveness of catheter-based
interventions in patients with narrowing of the renal artery has shown that angioplasty
and stenting offer no benefit over medical therapy. Among patients who completed one year
of follow-up, there were no differences in the change in kidney function, blood pressure
control or the rates of major cardiovascular illness, according to the Angioplasty and
Stenting for Renal Artery Lesions trial.
http://www.eurekalert.org/pub_releases/2008-04/wsw-ras033108.php
New study shows that lower food
intake has a negative effect on immune system
Researchers studying deer mice have discovered evidence to support what mothers everywhere
have long suspected: the immune system needs food to function properly. In an article
titled “Food Restriction Compromises Immune Memory in Deer Mice (Peromyscus
maniculatus) By Reducing Spleen-Derived Antibody-Producing B-Cell Numbers,” Lynn
Martin and coauthors find that reduced food intake leads to a decline in immune function
in their subjects. The findings, which will be published in the May/June 2008 issue of
Physiological and Biochemical Zoology, could have profound implications for human health.
http://www.eurekalert.org/pub_releases/2008-04/uocp-ftc033108.php
Prebiotics -- the key to fewer food
poisoning stomach upsets -- and healthy farm animals
Natural sugars found in breast milk that are now included in prebiotic foods may help in
the fight against Salmonella and other food poisoning bacteria, scientists heard
Wednesday, April 2, 2008 at the Society for General Microbiology's 162nd meeting being
held this week at the Edinburgh International Conference Centre.
http://www.eurekalert.org/pub_releases/2008-04/sfgm-pt032908.php
Early-onset obesity in father
linked to increased potential for liver disease in child
A history of early-onset paternal obesity increases the odds of elevated liver enzyme
levels in offspring and points to the potential for a genetic link between obesity and
liver disease, according to a study in Gastroenterology.
http://www.gastro.org/wmspage.cfm?parm1=5121
Controlling your appetite requires
PI3K signaling
How much we want to eat, in other words our appetite, and how much energy we burn, are
both controlled by a hormone known as leptin. Leptin is made by fat tissue and it passes
through the circulation to the brain, where it modifies the activity of several types of
nerve cell, including POMC nerves, to signal to the body that it does not need to eat more
and that it needs to burn more energy. As obesity can be caused if leptin-mediated
signaling goes awry, much effort is being expended trying to identify the signaling
pathways activated by leptin. Joel Elmquist and colleagues, at the University of Texas
Southwestern Medical Center, Dallas, have provided new insight into the signaling pathways
by which leptin mediates its effects on POMC nerves in mice.
http://www.eurekalert.org/pub_releases/2008-04/joci-joe032708.php
Chemotherapy-induced anemia
increases risk of local breast cancer recurrence
Patients with breast cancer who developed anemia during chemotherapy had nearly three
times the risk of local recurrence as those who did not, according to a study published in
the April 1 issue of Clinical Cancer Research¸ a journal of the American Association for
Cancer Research. “We speculate that there may be an interaction between
chemotherapy/radiotherapy and anemia,” said lead researcher Peter Dubsky, MD, a
senior consultant in the department of surgery at the Medical University of Vienna,
Austria. “Both treatment modalities have been shown to be less effective in anemic
patients. Since we do not see the effect in terms of relapse-free survival, the
interaction with local adjuvant treatment may play a more important role.”Dubsky and
his colleagues from the Austrian Breast and Colorectal Cancer Study Group examined data
from a randomized, clinical trial comparing adjuvant hormonal treatment and tamoxifen with
the standard treatment of cyclophosphamide, methotrexate and 5-fluorouracil (CMF). All
women in the trial were premenopausal and had positive estrogen and/or progesterone
receptor status. Patients who underwent breast-conserving surgery received mandatory
radiation. Radiation was optional in women who underwent modified radical mastectomy.
http://www.aacr.org/home/about-us/news.aspx?d=977
Short, long sleep duration is
associated with future weight gain in adults
Both short and long sleeping times predict an increased risk of future body weight and fat
gain in adults.
http://www.aasmnet.org/Articles.aspx?id=806
New Study in the Journal SLEEP
Finds a Link Between Insomnia and Depression in Young Adults
A study published in the April 1 issue of the journal SLEEP confirms the persistent nature
of insomnia and the increased risk of subsequent depression among individuals with
insomnia. The study, conducted by Jules Angst, MD, of Zurich University Psychiatric
Hospital in Switzerland, focused on 591 young adults, whose psychiatric, physical, and
sleep symptoms were assessed with six interviews spanning 20 years. Four duration-based
subtypes of insomnia were distinguished: one-month insomnia associated with significant
distress, two-to-three-week insomnia, recurrent brief insomnia, and occasional brief
insomnia. According to the results, the annual prevalence of one-month insomnia increased
gradually over time, with a cumulative prevalence rate of 20 percent and a greater than
two-fold risk among women. In 40 percent of subjects, insomnia developed into more chronic
forms over time. Insomnia either with or without comorbid depression was highly stable
over time. Insomnia lasting two weeks or longer predicted major depressive episodes and
major depressive disorder at subsequent interviews. Seventeen to 50 percent of subjects
with insomnia lasting two weeks or longer developed a major depressive episode in a later
interview. “Pure” insomnia and “pure” depression were not
longitudinally related to each other, whereas insomnia comorbid with depression was
longitudinally related to both.
http://www.aasmnet.org/Articles.aspx?id=804
Study finds concerns with biofuels
Biofuels are widely considered one of the most promising sources of renewable energy by
policy makers and environmentalists alike. However, unless principles and standards for
production are developed and implemented, certain biofuels will cause severe environmental
impacts and reduce biodiversity -- the very opposite of what is desired.
http://www.blackwellpublishing.com/press/pressitem.asp?ref=1659
Lack of sleep can provoke
sleepwalking
Sleepwalkers are advised to keep a regular bedtime to avoid unwanted evening strolls,
according to research from the Université de Montréal. Somnambulism, which affects up to
four percent of adults, can cause mental confusion or bouts of amnesia in those affected
as they wander unresponsive to their environment. In a recent issue of the Annals of
Neurology, the official journal of the American Neurological Association, authors Antonio
Zadra, Mathieu Pilon and Jacques Montplaisir explain how they evaluated 40 suspected
sleepwalkers. Each was referred to the Sleep Research Centre at Sacré-Coeur Hospital, a
Université de Montréal teaching hospital, between August 2003 and March 2007. “Our
study found that sleep deprivation can precipitate sleepwalking in predisposed
individuals,” said lead investigator Antonio Zadra. “Sleepwalkers are best to
maintain a regular bedtime and avoid sleep deprivation if they wish to steer clear of
somnambulism.”
http://nouvelles.umontreal.ca/index.php?option=com_content
&task=view&id=1248&Itemid=206
Researchers identify a gene
responsible for cases of Lou Gehrig’s disease
A team of Canadian and French researchers has identified a novel gene responsible for a
significant fraction of ALS (sporadic amyotrophic lateral sclerosis) cases. ALS is
commonly referred to as Lou Gehrig’s disease, an incurable neuromuscular disorder
that affects motor neurons and leads to paralysis and death within one to five years.
Published in the current online edition of Nature Genetics, the study on 200 human
subjects with ALS was led by Doctors Guy Rouleau, Edor Kabashi, Paul Valdmanis of the
Research Centre of the Centre hospitalier de l'Université de Montréal (CRCHUM). The team
identified several genetic mutations in the TDP-43 gene by studying ALS patients from
France and Quebec. They established TDP-43 as the gene responsible for up to five percent
of the ALS patients. The breakthrough is the result of teamwork with peers from the
Waterloo and Laval universities in Canada and the Fédération des maladies du système
nerveux and the Institute of Biology (Unité de Neurologie Comportementale et
Dégénérative) in France.
http://nouvelles.umontreal.ca/content/view/1239/125/
Are blood thinners post-op killers?
Current US guidelines for the prescription of potent anticoagulants by surgeons who
perform joint replacement operations could be doing patients more harm than good,
according to Dr. Nigel Sharrock and his team from the Hospital for Special Surgery in New
York. Their paper was published in the March issue of Springer's journal Clinical
Orthopaedics and Related Research.
http://www.springer-sbm.com/index.php?id=291&backPID=
132&L=0&tx_tnc_news=4237&cHash=b873d59e22
Hospital Clínic conducts the first
kidney extraction through the vagina in Europe
A group of the Urology Service of the Hospital Clínic, led by Dr. Antonio Alcaraz, has
successfully conducted this intervention to a 66 year woman diagnosed with renal cancer.
The operation consisted in the extirpation of a kidney through the vagina (transvaginal
nephrectomy), assisted by laparoscopy. The novelty of this procedure achieved through
intensive works in experimental surgery resides in the fact that it does not leave
external scars, and that the recovery time is utterly reduced.
http://www.eurekalert.org/pub_releases/2008-03/i-id-hcc033108.php
Tai Chi exercises improve type 2
diabetes control
Tai Chi exercises can improve the control of type 2 diabetes, suggests a small study,
published ahead of print in the British Journal of Sports Medicine.
http://www.eurekalert.org/pub_releases/2008-03/bmj-tce033108.php
New research provides insight into
menopause
Insight into why females of some species undergo menopause while others do not has proven
elusive despite an understanding of the biological mechanisms behind the change. However,
new research by scientists at the Universities of Cambridge and Exeter suggests that
menopause is an adaptation to minimize reproductive competition between generations of
females in the same family unit.
http://www.admin.cam.ac.uk/news/dp/2008040101
No benefit found from continuing
neuroleptic drugs in Alzheimer's patients
Results of a randomized trial published in PLoS Medicine show no benefit in cognitive or
neuropsychiatric outcomes from continuing neuroleptic drugs in patients with Alzheimer's
disease.
http://www.eurekalert.org/pub_releases/2008-03/plos-nbf032708.php
A new way to fight cancer - the
silver shield
A unique study proposes a new paradigm in cancer treatment: instead of selectively
attacking cancer cells, protect all the healthy cells. Animal studies and in vitro human
cell studies show that a short fast protects healthy cells against chemotherapy, while
tumor cells remain sensitive to the drugs.
http://www.usc.edu/uscnews/stories/15032.html
Hormone that controls hunger and
appetite also linked to reduced fertility
Researchers at Yale School of Medicine have found that in-utero exposure to the hormone
grhelin, a molecule that controls appetite and hunger and nutrition, can result in
decreased fertility and fewer offspring.
http://www.yale.edu/opa/newsr/08-03-28-02.all.html
Study Shows Why Synthetic Estrogens
Wreak Havoc on Reproductive System
Researchers at Yale School of Medicine now have a clearer understanding of why synthetic
estrogens such as those found in many widely-used plastics have a detrimental effect on a
developing fetus, cause fertility problems, as well as vaginal and breast cancers.
Preliminary results of the study will be presented at the 2008 Society for Gynecologic
Investigation (SGI) Annual Scientific Meeting held March 26-29 in San Diego, California.
The study was led by Hugh S. Taylor, M.D., professor in the Department of Obstetrics,
Gynecology & Reproductive Science and section chief of Reproductive Endocrinology and
Infertility at Yale School of Medicine. Past research shows that exposure to the synthetic
estrogen diethylstilbestrol (DES) alters the expression of HOXA10, a gene necessary for
uterine development, and increases the risk of cancer and pregnancy complications in
female offspring.Pregnant women are frequently exposed to other similar substances with
estrogen-like properties, such as Bisphenol-A (BPA). BPA is found in common household
plastics and has recently been linked to long-term fertility problems. Like DES, these
other substances may also impact female reproductive tract development and the future
fertility of female fetuses.
http://www.yale.edu/opa/newsr/08-03-28-03.all.html
Chiropractor May Help Lower Blood
Pressure
Chiropractor May Help Lower Blood PressureMillions of Americans take medication to lower
their blood pressure. But new research suggests there may be a better way by tossing the
pills and heading to a chiropractor.
http://www.thedenverchannel.com/video/15706982/index.html
Increasing access to antiretroviral
drugs would drastically cut AIDS deaths in South Africa
More that 1.2 million deaths could be prevented in South Africa over the next five years
by accelerating efforts to provide access to antiretroviral therapy, according to a study
released online today by the Journal of Infectious Diseases.
http://www.massgeneral.org/news/releases/032608walensky.html
Study shows the upside of anger
Here's a maxim from the "duh" department - People typically prefer to feel
emotions that are pleasant, like excitement, and avoid those that are unpleasant, like
anger. But a new study appearing in the April issue of Psychological Science, a journal of
the Association for Psychological Science, says this may not always be the case.
http://www.psychologicalscience.org/media/releases/2008/tamir.cfm
Painkillers, inflammation
inhibitors, anti-cancer drugs and new de-methylating agents
Researchers at the National Sun Yat-Sen University and Kaohsiung Medical University,
Kaohsiung, Taiwan have revealed a new mechanism by which nonsteroidal anti-inflammatory
drugs (NSAIDs) attenuate tumor invasion and metastasis. The research, to be published in
the April 2008 issue of Experimental Biology and Medicine, provides new insights for the
understanding of the anti-cancer effects of NSAIDs. NSAIDs have been used for the
suppression of pain and inflammation in the clinic for many years. The main targets of
these drugs are cyclooxygenases (COXs) which play critical roles in maintaining
physiological homeostasis, mediating inflammatory reactions and promoting tumorigenesis.
However, COX-independent effects are also important for the inhibition of cancer
development by NSAIDs. Indeed, NSAIDs are considered as a novel class of effective
chemopreventive drugs. The research team, led by Wen-Chun Hung, Dean of College of
Science, National Sun Yat-Sen University, and a recent doctorial graduate Mei-Ren Pan and
two collaborators Hui-Chiu Chang and Lea-Yea Chuang of Kaohsiung Medical University found
that NSAIDs up-regulated several anti-metastatic genes including secreted protein acidic
and rich in cysteine (SPARC), thrombospindin-1 (TSP-1), TSP-3 and tissue inhibitors of
metalloproteinase-2 (TIMP-2) in human lung cancer cells. “Our functional assay
suggested that increases of SPARC and other anti-metastatic genes were important for
NSAIDs to inhibit tumor invasion and metastasis” said Wen-Chun Hung. “More
importantly, we elucidated the underlying mechanism and demonstrated that up-regulation of
SPARC in human lung cancer cells was mediated via inhibition of DNA methyltransferases
(DNMTs) expression and promoter de-methylation. This is the first report to show that
NSAIDs may inhibit the expression of DNMTs to reverse promoter methylation and to
reactivate gene transcription.”
http://www.eurekalert.org/pub_releases/2008-03/sfeb-npi032608.php
Umbilical cord blood cell therapy
may reduce signs and symptoms of Alzheimer's disease
Targeted immune suppression using human umbilical cord blood cells significantly improved
Alzheimer's-like brain damage in a mouse model of the neurodegenerative disease, a new
study reports.
http://hscweb3.hsc.usf.edu/health/now/?p=422
Dental chair a possible source of
neurotoxic mercury waste
Researchers have found evidence suggesting that bacteria that methylate mercury and make
the metal a potent neurotoxin thrive in waste water downstream from dental clinics and
offices. The researchers believe engineering solutions can be developed to quell public
health concerns.
http://tigger.uic.edu/htbin/cgiwrap/bin/newsbureau/cgi-bin/index.cgi?from=
Releases&to=Release&id=2133&start=1198822299&end=1206598299&topic=0&dept=0
Key factor in brain development
revealed, offers insight into disorder
In the earliest days of brain development, the brain's first cells – neuroepithelial
stem cells -- divide continuously, producing a population of cells that eventually evolves
into the various cells of the fully formed brain. Now, UCSF scientists have identified a
gene that, in mice, is critical for these stem cells to divide correctly. Without it, they
fail to divide, and die.
http://pub.ucsf.edu/newsservices/releases/200803262/
Large multicenter study suggests
new genetic markers for Crohn's disease
What is believed to be the largest study of its kind for the genetic roots of inflammatory
bowel diseases has suggested new links to Crohn's disease as well as further evidence that
some people of Jewish descent are more likely to develop it.
http://www.eurekalert.org/pub_releases/2008-03/jhmi-lms032608.php
Study validates Pittsburgh
Compound-B in identifying Alzheimer's disease brain toxins
A groundbreaking study conducted by University of Pittsburgh Alzheimer's disease
researchers reported in the journal Brain (currently online) confirms that Pittsburgh
Compound-B binds to the telltale beta-amyloid deposits found in the brains of patients
with Alzheimer's disease. The finding is a significant step toward enabling clinicians to
provide a definitive diagnosis of Alzheimer's disease in living patients.
http://www.upmc.com/Communications/MediaRelations/
NewsReleaseArchives/2008/March/BrainPiB.htm
Basis created for directing and
filming blood vessels
A new method of filming blood-vessel cells that move in accordance with targeted signals
has been developed by researchers at Uppsala University in collaboration with researchers
at the University of California. The method can also be used to study how migration of
cancer cells and nerves can be controlled. These interesting findings have now been
published in the Journal of Biological Chemistry.
http://www.uu.se/news/news_item.php?typ=press&id=116
Apple pectin, apple juice extracts
shown to have anticarcinogenic effects on colon
The apples and apple juice you consume may have positive effects in in the colon. New
research has demonstrated that both apple pectin and polyphenol-rich apple juice
components actually enhance biological mechanisms that produce anticarcinogenic compounds
during the fermentation process.
http://www.eurekalert.org/pub_releases/2008-03/uaa-apa032608.php
Brain scientist shedding light on
learning, memory
Neurons spoke to Dr. Joe Z. Tsien when he was a sophomore college student searching for
some meaningful extracurricular activity. He had stopped by the lab of a brain researcher
at Shanghai's East China Normal University. The room was dark except for a light shining
on the brain. "You could hear this pop, pop, pop, pop," says Dr. Tsien, brain
scientist who recently came to the Medical College of Georgia from Boston University.
"At that moment, I got interested in the brain."
https://my.mcg.edu/portal/page/portal/494AA8A8CB7B2366E0440003BAD149FF
Growth hormone found to have new
role in development of brain's smell center
Insulin-like growth factor has to date been shown to stimulate the growth and
proliferation of cells, and recently was found to affect the shape and growth rate of
nerve axons. Now, UC Berkeley neuroscientist John Ngai and colleagues have shown that IGF
also controls the direction of axon growth as axons stretch from the nose's odor detectors
to the brain's olfactory bulb. Axon guidance represents a new role for IGF in development.
http://www.berkeley.edu/news/media/releases/2008/03/26_ngai.shtml
Study shows compassion meditation
changes the brain
Can we train ourselves to be compassionate? A new study suggests the answer is yes.
Cultivating compassion and kindness through meditation affects brain regions that can make
a person more empathetic to other peoples' mental states, say researchers at the
University of Wisconsin-Madison.
http://www.news.wisc.edu/14944
Coronary calcium testing predicts
future heart ailments
Calcium deposits in coronary arteries provide a strong predictor for possible future heart
attacks and cardiac diseases, and detecting such deposits can be valuable for promoting
overall cardiac health, according to a study led by the University of California, Irvine,
and appearing in the March 28 issue of the New England Journal of Medicine.
http://today.uci.edu/news/release_detail.asp?key=1747
Epilepsy marked by neural 'hub'
network
An increased number of neuron “hubs” in the epileptic brain may be the root
cause for the seizures that characterize the disorder, according to a UC Irvine study.
Researchers Robert Morgan and Ivan Soltesz with the Department of Anatomy and Neurobiology
identified that these hubs – a small number of highly connected neurons – are
formed in the hippocampus during the transition from a healthy brain to an epileptic one.
The increased number of connections among these hubs, they found, circulate and amplify
signals to such a degree that they overwhelm brain networks, leading to epileptic
seizures.
http://today.uci.edu/news/release_detail.asp?key=1749
Brain's 'sixth sense' for calories
discovered
The brain can sense the calories in food, independent of the taste mechanism, researchers
have found in studies with mice. Their finding that the brain's reward system is switched
on by this "sixth sense" machinery could have implications for understanding the
causes of obesity. For example, the findings suggest why high-fructose corn syrup, widely
used as a sweetener in foods, might contribute to obesity.
http://www.eurekalert.org/pub_releases/2008-03/cp-bs032008.php
Kaiser Permanente study shows that
a larger abdomen in midlife increases risk of dementia
A Kaiser Permanente study shows that people in their 40s with larger stomachs have a
higher risk for dementia when they reach their 70s. Previous studies showed that a large
abdomen in midlife increases the risk of diabetes, stroke, and heart disease, but this is
the first time researchers demonstrated that it also increases the risk of dementia.
Researchers measured belly fat on 6,583 people ages 40 to 45, then followed them 36 years
later.
http://www.eurekalert.org/pub_releases/2008-03/kpdo-kps031908.php
Larger belly in mid-life increases
risk of dementia
People with larger stomachs in their 40s are more likely to have dementia when they reach
their 70s, according to a study published in the March 26, 2008, online issue of
Neurology, the medical journal of the American Academy of Neurology.
http://www.aan.com/press/index.cfm?fuseaction=release.view&release=585
Multi-institutional study
identifies new form of inherited risk of cancer
Like the subtext of a novel, the human genome sequence harbors more information than
appears just in its "letters" of A, C, T and G. Since DNA is a data-packed
molecule passed from generation to generation, comparing genome sequences among
individuals also holds clues to ancestry.
http://news.med.cornell.edu/wcmc/wcmc_2008/03_25_08.shtml
UCLA researchers examine human
embryonic stem cell genome
Stem cell researchers from UCLA used a high resolution technique to examine the genome, or
total DNA content, of a pair of human embryonic stem cell lines and found that while both
lines could form neurons, the lines had differences in the numbers of certain genes that
could control such things as individual traits and disease susceptibility.
http://www.eurekalert.org/pub_releases/2008-03/uoc--ure032708.php
Hope among patients with ALS may
take a variety of forms
Sustaining hope in the face of a chronic, debilitating illness such as amyotrophic lateral
sclerosis should be a goal of palliative care and can take many forms, representing a
continuum from focusing on the self to concern for others, as described in a paper
published in the April issue of Journal of Palliative Medicine, a peer-reviewed
publication of Mary Ann Liebert, Inc.
http://www.liebertpub.com/prdetails.aspx?pr_id=629
Normal weight obesity - An emerging
risk factor for heart and metabolic problems
The researchers defined "normal weight" by body mass index. They found that
people with normal BMI who had the highest percentage of body fat were also those who had
metabolic disturbances linked to heart disease.
http://www.mayoclinic.org/news2008-rst/4738.html
U of T research finds glycine could
be key to REM Sleep Behavior Disorder
New research out of U of T holds promise for thousands who suffer from REM Sleep Behavior
Disorder.
http://www.eurekalert.org/pub_releases/2008-03/uot-uot032708.php
Risks of increased access to
over-the-counter medicines may outweigh benefits
The risks of increasing people's access to over-the-counter medicines may outweigh the
benefits, warn experts in this week’s BMJ.
http://www.eurekalert.org/pub_releases/2008-03/bmj-roi032708.php
Family study bolsters link between
pesticides and Parkinson's
For the first time, the association between Parkinson's disease and exposure to pesticides
has been shown in patients with the neurological disorder compared with their unaffected
relatives, according to a study in the online open access journal BMC Neurology.
http://www.eurekalert.org/pub_releases/2008-03/bc-fsb032608.php
Evaluation of the current knowledge
limitations in breast cancer research
Gaps were identified in all seven themes. General barriers to progress were lack of
financial and practical resources, and poor collaboration between disciplines. Critical
gaps in each theme included (1) genetics: knowledge of genetic changes, their effects and
interactions; (2) initiation of breast cancer: how developmental signalling pathways cause
ductal elongation and branching at the cellular level and influence stem cell dynamics,
and how their disruption initiates tumour formation; (3) progression of breast cancer:
deciphering the intracellular and extracellular regulators of early progression, tumour
growth, angiogenesis and metastasis; (4) therapies and targets: understanding who develops
advanced disease; (5) disease markers: incorporating intelligent trial design into all
studies to ensure new treatments are tested in patient groups stratified using biomarkers;
(6) prevention: strategies to prevent oestrogen-receptor negative tumours and the
long-term effects of chemoprevention for oestrogen-receptor positive tumours; (7)
psychosocial aspects of cancer: the use of appropriate psychosocial interventions, and the
personal impact of all stages of the disease among patients from a range of ethnic and
demographic backgrounds.
http://breast-cancer-research.com/content/10/2/R26
Scientists find a key culprit in
stroke brain cell damage
Researchers have identified a key player in the killing of brain cells after a stroke or a
seizure. The protein asparagine endopeptidase unleashes enzymes that break down brain
cells' DNA, scientists at Emory University School of Medicine have found.
http://www.eurekalert.org/pub_releases/2008-03/eu-sfa032508.php
Rates of rare mutations soar 3 to 4
times higher in schizophrenia
People with schizophrenia have high rates of rare genetic deletions and duplications that
likely disrupt the developing brain. These anomalies were found in 15 percent of adult
onset schizophrenia patients and 20 percent of child and adolescent onset patients,
compared with only 5 percent of healthy participants. Collectively, the mutations carried
by patients were significantly more likely than those in healthy participants to disrupt
genes involved in brain development -- potentially implicating hundreds of genes.
http://www.nimh.nih.gov/science-news/2008/rates-of-rare-
mutations-soar-three-to-four-times-higher-in-schizophrenia.shtml
Elevated markers of maternal
cardiovascular risk persist even 10 years after preterm birth
Women with a previous preterm birth had higher concentrations of total cholesterol than
women whose babies were born at term, and those whose babies were born earliest –
less than 34 weeks gestation – had the highest concentrations, Janet M. Catov, Ph.D.,
and her colleagues report. “Women with preterm birth are at increased risk for
cardiovascular disease, but mechanisms relating to these conditions are not well
understood,” said Dr. Catov, assistant professor of obstetrics, gynecology and
reproductive sciences at Pitt and an investigator at MWRI. “We wanted to see whether
some of these cardiovascular risk factors observed during pregnancy persist into the
postpartum period. Dr. Catov and her colleagues compared information on 47 women who had
delivered prior to 37 weeks gestation with data on 104 women with term births, at or more
than 37 weeks gestation. Concentrations of total cholesterol, triglycerides, LDL and HDL
also were collected an average of 7.4 years postpartum and compared. “We found that
total cholesterol was an average of two to three times higher for women with a history of
preterm birth compared to those with normal gestation births,” said Dr. Catov, adding
that results were similar for LDL and HDL cholesterol, even after adjustment for race,
age, smoking and body weight.
http://www.eurekalert.org/pub_releases/2008-03/uops-whs032508.php
Study Confirms Validity of
Pittsburgh Compound-B in Identifying the Toxins Associated with Alzheimer’s Disease
A groundbreaking study conducted by University of Pittsburgh Alzheimer’s disease
researchers reported in the journal Brain (currently online) confirms that Pittsburgh
Compound-B (PiB) binds to the telltale beta-amyloid deposits found in the brains of
patients with Alzheimer’s disease. The finding is a significant step toward enabling
clinicians to provide a definitive diagnosis of Alzheimer’s disease in living
patients.
http://www.upmc.com/Communications/MediaRelations/
NewsReleaseArchives/2008/March/BrainPiB.htm
Are you what you eat? New study of
body weight change says maybe not
If identical twins eat and exercise equally, must they have the same body weight? By
analyzing the fundamental equations of body weight change, NIH investigators Carson Chow
and Kevin Hall find that identical twins with identical lifestyles can have different body
weights and different amounts of body fat.
http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1000045
Statins Impair Antitumor Effects of
Rituximab by Inducing Conformational Changes of CD20
Statins were shown to interfere with both detection of CD20 and antilymphoma activity of
rituximab. These studies have significant clinical implications, as impaired binding of
mAbs to conformational epitopes of CD20 elicited by statins could delay diagnosis,
postpone effective treatment, or impair anti-lymphoma activity of rituximab.
http://medicine.plosjournals.org/perlserv/?request=get-document
&doi=10.1371/journal.pmed.0050064
The Potential Effect of Statins on
Rituximab Immunotherapy
Assuming long-term statin treatment does indeed substantially reduce CD20 detection in
vivo, two obvious changes to clinical management should be made. First, extensive use of
statins for the treatment of hypercholesterolemia should be a contraindication for the use
of CD20 as a diagnostic marker for mature B cells. Second, statins should be removed from
the treatment of patients with either malignant or autoimmune disease who are required to
undergo CD20-specific therapy.
http://medicine.plosjournals.org/perlserv/?request=get-document&
doi=10.1371/journal.pmed.0050077
A new method to identify mutated
genes in human diseases
Researchers from the University of Turin, Italy and the University of Nijmegen, the
Netherlands, have devised a new method that may help the medical community to determine
the genetic basis of many common diseases. Their findings are described in an article
published March 21 in the open-access journal PLoS Computational Biology.
http://www.eurekalert.org/pub_releases/2008-03/plos-anm031408.php
Folate scores a win in animal
studies - Brief, high doses of B vitamin blunt damage from heart attack
Long known for its role in preventing anemia in expectant mothers and spinal birth defects
in newborns, the B vitamin folate, found in leafy green vegetables, beans and nuts has now
been shown to blunt the damaging effects of heart attack when given in short-term, high
doses to test animals.
http://www.hopkinsmedicine.org/Press_releases/2008/03_27_08.html
A ton of bitter melon produces
sweet results for diabetes
Scientists have uncovered the therapeutic properties of bitter melon, a vegetable and
traditional Chinese medicine, that make it a powerful treatment for Type 2 diabetes. Teams
from the Garvan Institute of Medical Research and the Shanghai Institute of Materia Medica
pulped roughly a tonne of fresh bitter melon and extracted four very promising bioactive
components. These four compounds all appear to activate the enzyme AMPK, a protein well
known for regulating fuel metabolism and enabling glucose uptake. The results are
published online today in the international journal Chemistry & Biology. “We can
now understand at a molecular level why bitter melon works as a treatment for
diabetes,” said Professor David James, Director of the Diabetes and Obesity Program
at Garvan. “By isolating the compounds we believe to be therapeutic, we can
investigate how they work together in our cells.” People with Type 2 diabetes have an
impaired ability to convert the sugar in their blood into energy in their muscles. This is
partly because they don’t produce enough insulin, and partly because their fat and
muscle cells don’t use insulin effectively, a phenomenon known as ‘insulin
resistance’. Exercise activates AMPK in muscle, which in turn mediates the movement
of glucose transporters to the cell surface, a very important step in the uptake of
glucose from the circulation into tissues in the body. This is a major reason that
exercise is recommended as part of the normal treatment program for someone with Type 2
diabetes. The four compounds isolated in bitter melon perform a very similar action to
that of exercise, in that they activate AMPK.
http://www.eurekalert.org/pub_releases/2008-03/ra-ato032608.php
Infant formula must contain DHA
omega-3 and AA omega-6, say international experts
New recommendations published by international experts in the Journal of Perinatal
Medicine state that infant formula should include DHA omega-3 and AA omega-6 to guarantee
a correct eye and brain development.
http://www.eurekalert.org/pub_releases/2008-03/udg-ifm032608.php
Stem cells from hair follicles may
help 'grow' new blood vessels
For a rich source of stem cells to be engineered into new blood vessels or skin tissue,
clinicians may one day look no further than the hair on their patients' heads, according
to new research published earlier this month by University at Buffalo engineers.
http://www.buffalo.edu/news/9287
Mysterious fevers of unknown origin
- Could surgery be a cure?
A child spikes a high fever like clockwork every 3-6 weeks, sometimes as high as 104 or
105 degrees, and sometimes causing seizures. No infection or any other cause is ever
found. Yet, according to a report in the Archives of Otolaryngology and Head and Neck
Surgery, tonsillectomy is almost always curative. The reason remains a mystery, but
desperate families are opting for surgery as a last-ditch measure and finding it to be
life-changing.
http://www.childrenshospital.org/newsroom/Site1339/
mainpageS1339P1sublevel409.html
Removal of an inflamed appendix
through a patient's vagina
On March 26, 2008, surgeons at UC-San Diego Medical Center removed an inflamed appendix
through a patient's vagina, a first in the United States. Patient Diana Schlamadinger,
reported only minor discomfort. Key to these surgical clinical trials is collaboration
with medical device companies to develop new minimally-invasive tools.
http://www.eurekalert.org/pub_releases/2008-03/uoc--a032808.php
Potential new target for multiple
sclerosis therapy
Researchers demonstrate both genetic and pharmaceutical evidence for the role of a protein
called collagenase-2 in the development of multiple sclerosis (MS), providing a potential
new way to combat this debilitating disease.
http://www.eurekalert.org/pub_releases/2008-03/asfb-pnt032808.php
LDL particle measurement by NMR
recognized by ADA, ACC
The American Diabetes Association and the American College of Cardiology issued a
consensus statement today that states the measurement of LDL particle number by nuclear
magnetic resonance is one of the more accurate ways to evaluate cardiometabolic risk. The
study, published in the April issue of Diabetes Care, reinforces that LDL cholesterol may
not be the best way to quantify a patient's risk for cardiovascular disease.
http://www.eurekalert.org/pub_releases/2008-03/dgpr-lpm032808.php
Big Tobacco Funding for Cancer
Research Decried
A leading lung cancer researcher received funding from a tobacco company and failed to
disclose the source of her funding in published studies, according to reports in two
publications.
http://www.abcnews.go.com/Health/story?id=4529526&page=1
Are Teenage Brains Really
Different?
MRI Studies Show Brain Changes in the Adolescent Brain Impact Cognition, Emotion and
BehaviorMany parents are convinced that the brains of their teenage offspring are
different than those of children and adults. New data confirms that this is the case. An
article by Jay N. Giedd, MD, of the National Institute of Mental Health (NIMH), published
in the April 2008 issue of the Journal of Adolescent Health describes how brain changes in
the adolescent brain impact cognition, emotion and behavior. Dr. Giedd reviews the results
from the NIMH Longitudinal Brain Imaging Project. This study and others indicate that gray
matter increases in volume until approximately the early teens and then decreases until
old age. Pinning down these differences in a rigorous way had been elusive until MRI was
developed, offering the capacity to provide extremely accurate quantifications of brain
anatomy and physiology without the use of ionizing radiation.
http://www.alphagalileo.org/index.cfm?fuseaction=
readrelease&releaseid=528225&ez_search=1
The Immune System and Cancer - New
Insights into a Not Always Healthy Interplay
For a long time, scientists believed that the immune system acted to fight cancer
development. However, recent findings demonstrate that the immune system also acts to
promote cancer progression. At the International conference “Invasion and
Metastasis” held at the Max Delbrück Center for Molecular Medicine (MDC) in Berlin,
Dr. David DeNardo from the laboratory of Professor Lisa Coussens from the University of
California, San Francisco, USA reported on how tumours use immune cells to grow faster and
disseminate in the body. When germs infiltrate a wound after injury, the body can well
defend itself. Immune cells recognize the pathogens and initiate inflammation to limit
infection. Attracted by this warning, many different cells of the immune system migrate to
the centre of inflammation to help fight off the intruders. The injured area gets hot and
red and becomes more sensitive and swollen. When the healing process is completed,
inflammation abates and the immune cells withdraw. When some types of immune cells
encounter tumour cells, they can also cause inflammation. Compared to normal injury,
however, these immune cells often do not withdraw, but rather generate an enduring,
chronic inflammation. “Therefore, we call tumours wounds that never heal,” Dr.
DeNardo illustrated.
http://www.alphagalileo.org/index.cfm?fuseaction=
readrelease&releaseid=528209&ez_search=1
Polar Body Diagnosis – A Step
in the Right Direction?
Polar body diagnosis can make artificial fertilization more successful, according to
Katrin and Hans van der Ven and Markus Montag of Bonn University Clinic, writing in the
current edition of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2008; 105[11]
190-6). If the two polar bodies in an egg cell are examined, it can be seen whether the
chromosomes are damaged or whether the positions of the chromosomes are abnormal. This
should help to prevent pregnancies and births of severely ill children and lead to higher
implantation and birth rates. Preimplantation diagnosis (PID) on the individual cells of a
developing embryo allows the hereditary material to be examined directly. In Germany, PID
is thought to be incompatible with the German Embryo Protection Act. This is why polar
body diagnosis has become established in parallel to the debate on ethical and legal
issues. In the accompanying editorial, the human geneticist Peter Propping asks whether it
is honest that German doctors continue to draw on PID results obtained abroad to compare
the reliability of polar body diagnosis.
http://www.aerzteblatt-international.de/v4/archiv/pdf.asp?id=59402
Mobile Cancer Stem Cells – The
Real Bad Guys? - New Model of Metastasis Formation Presented in Berlin
Mobile cancer stem cells can form metastases in colon cancer and other malignant tumours.
Professor Thomas Brabletz from the University Hospital Freiburg, Germany, has developed a
new model, which he presented at the International Conference “Invasion and
Metastasis” held at the Max Delbrück Center for Molecular Medicine (MDC) in Berlin.
“Therefore, mobile cancer stem cells are the most dangerous cells for cancer
patients,” he said. Until recently researchers assumed that every single tumour cell
could form metastases. According to the World Health Organization, 655,000 people die from
colon cancer every year. After lung cancer, it is the second most common cause of
cancer-related deaths. This type of cancer arises from glands of the colon mucosa. It
often goes unnoticed during the initial stage of development. Indeed, affected patients
rarely present with pain or other symptoms, and thus the cancer is often not spotted until
dangerous metastases have already developed. Cancer stem cells in colon cancer develop
from colon stem cells, Professor Brabletz stated. These stem cells normally ensure that
colon cells, which have a very short life span, are replaced each day. When such a stem
cell becomes a cancer stem cell, it can divide infinitely and produce more cancer stem
cells. In the second step of development, the altered cell detaches from the primary
tumour and is then able to disseminate through blood or lymphatic vessels in the body.
http://www.alphagalileo.org/index.cfm?fuseaction=r
eadrelease&releaseid=528187&ez_search=1
Malaria Infection Of The Liver And
In Pregnancy - Two Key Studies By Igc Researchers
In two papers published in February and March in the journal PLoS ONE(*), scientists at
the Instituto Gulbenkian de Ciência (IGC), in Portugal, have produced important findings
towards better understanding malaria infection of the liver, and during pregnancy. Carlos
Penha-Gonçalves and his team, at the Disease Genetics Laboratory, have developed an
authentic mouse model of severe malaria in pregnant women. In a separate study, the group
identified a genetic region which makes mice less vulnerable to infection of the liver by
malaria parasites. It is estimated that over 50 million pregnancies occur each year in
malaria endemic areas. Indeed, pregnancy-associated malaria is one of the major public
health burdens in Africa, leading to 100,000 infant deaths annually. Pregnant women who
are infected with the Plasmodium parasite show more critical symptoms of malaria, their
pregnancies rarely go to term, the growth of the fetus is delayed, babies have low birth
weight and often die during infancy. Carlos and his team have now developed a mouse model
of pregnancy-induced malaria which reliably recapitulates the symptoms of the disease,
both in the mother and in the fetus. Using this mouse model, the researchers have already
begun to unpick some of the events which may underlie the severity of malaria infection
during pregnancy.
http://www.alphagalileo.org/index.cfm?fuseaction=r
eadrelease&releaseid=528161&ez_search=1
Don’t Offend Others With
Second-Hand Chemicals
Feel overwhelmed by cleaning tasks? There's one way to actually take control over the
toxins that may be stressing out your nervous and detoxification systems – stop using
chemicals on your body and in your house. You'll also be doing your family, friends,
neighbors and the environment a favor by not putting chemical fumes in the air.
http://www.naturalnews.com/022902.html
New Understanding of the Role of
Testosterone in Women
Testosterone conveys powerful anti-aging effects. It turns fat into muscle, keeps skin
supple, increases bone mineral density, gives us positive mood, and boosts our ability to
handle stress. It supports cognitive functioning, and keeps the liver and blood vessels
clean. Low testosterone levels have been associated with heart attack, Alzheimer's
disease, osteoporosis, and depression. If you are freezing cold all the time and your
thyroid levels are adequate, you are probably low on testosterone. For women, a little bit
of testosterone can go a long way in improving looks, figure, energy level, outlook on
life, enjoyment of living, sex appeal and sexual fulfillment.
http://www.naturalnews.com/022900.html
Tracing Pesticides in Children From
Ingestion to Elimination
If a child eats conventionally grown produce, will it affect his or her health? Recent
research revealed that pesticides do show up in the urine of children after consuming
non-organic foods. Though the study did not look at whether or not some of the chemicals
stay in the tissues and cause damage, other research says they do.
http://www.naturalnews.com/022897.html
The End of Antibiotics
Eventually antibiotics are going to be seen as one of the worst things to ever come out of
pharmaceutical science because in the end, they have made us only weaker in the face of
ever increasingly strong super bugs that are resistant to all the antibiotics doctors have
at their disposal. When we look at how deep the rabbit hole goes with antibiotics, we will
get sick in our souls. Antibiotics have fulfilled their anti–biotic anti-life role
leaving a long trail of death and suffering in the wake of their use.
http://www.naturalnews.com/022897.html
Compact Fluorescent Light Bulbs May
Be Hazardous to Your Health
Breaking a CFL can cause serious health risks. They contain mercury. This is especially
hazardous for small children and pregnant women. They also warn that these light bulbs
should never be used over carpeted surfaces because in the event of breakage, the mercury
could contaminate the carpet necessitating completely removing portions of the carpet to
eliminate the mercury hazards.
http://www.naturalnews.com/022886.html
Sore Wrists and Hands Can Result
from Our Work: but Is It Carpal Tunnel Syndrome?
An estimated 2 million people in the United States are affected by carpal tunnel syndrome,
according to the AANS. About half of all cases are work-related, and in fact, carpal
tunnel syndrome accounts for the highest average number of days missed at work, when
compared to all other work-related injuries or illnesses.
http://www.newswise.com/articles/view/539127/
"False" cancer results
exposed
Scans given to women who have a high risk of inheriting breast cancer falsely give a
positive result for the disease in five out of six cases, new research shows.
http://www.nursinginpractice.com/default.asp?title=%22False%22
cancerresultsexposed&page=article.display&article.id=9573
Enviro-toxins, radiation may be
tied to breast cancer
Produced by the Breast Cancer Fund, a nonprofit group whose mission is to identify
environmental links to breast cancer, "The State of the Evidence: 2008"
concludes toxic chemicals in the environment, along with increased radiation exposure, are
the main culprits in the sharp rise of breast cancer incidence.
http://www.news-press.com/apps/pbcs.dll/article?AID=/
20080325/MOMS/803250310/1013/LIFESTYLES
MMR and mercury detox - how to
protect your child
The latest views about children with autism is that it is a multifactorial problem, due to
a combination of vaccination, heavy-metal exposure and even to microwaves, as generated by
mobile phones. Typically, a child exhibits gut conditions, problems with detoxification
and heavy-metal poisoning. Here are a few basic ways to regularize these symptoms.
http://community.wddty.com/blogs/lynnemctaggart/archive/2008/03/25/
MMR-and-mercury-detox_3A00_-how-to-protect-your-child.aspx
CSPI warns about coffee creamers
Choosing a creamer over milk with your office coffee could mean you consume far more
saturated fat than you think, the Center for Science in the Public Interest has warned.
http://www.foodnavigator-usa.com/news/ng.asp?n=
84197-cspi-nestle-coffee-creamers-saturated-fat
Chile under fire for results of
intensive salmon fish farms
On a recent visit to a port south of Puerto Montt, a warehouse contained hundreds of bags,
some as large as 1,250 kilograms, or 2,750 pounds, filled with salmon food and medication.
The bags - many of which were labeled "Marine Harvest" and "medicated
food" for the fish - contained antibiotics and pigment as well as hormones to make
the fish grow faster, said Adolfo Flores, the port director.
http://www.iht.com/articles/2008/03/26/america/salmon.php
What’s an ideal BP?
An eminent kidney specialist from Italy Prof Jiani Kaipaso advocated the use of Soda
(Sodium bicarbonate) as a substitute to normal salt (sodium chloride) saying the latter
caused more harm to kidneys. "The kidney cells get more damaged with normal salt
while soda almost does no damage nor raise the BP level," he said. "Normal salt
if taken in less or higher quantity does affect the kidneys and has to be substituted with
Soda (sodium bicarbonate)," Kaipaso said.
http://www.merinews.com/catFull.jsp?articleID=131215
GM Corn to Make Men Sterile Already
a Reality
Since 1973 the World Health Organization has been looking for ways to use vaccines and
injections to control the world’s fertility. If those methods are offered to men and
women so that they can make a choice about their reproductive lives, well and good. If,
however, they are hidden in smallpox vaccines (Africa) with the avowed purpose of
“eliminating 150 million excess Sub Saharan Africans” as they were in vaccines
distributed by the WHO starting in 1985, or in tetanus vaccines which would cause
abortions in South and Central America women starting in the 1990’s, we are not
dealing with reproductive options, but reproductive genocide.
http://www.healthfreedomusa.org/?p=563
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